B
BUDDSBarnet Unified Document
for Down Syndrome

Nutrivene - D and UK Perspective

UK DSMIG research evidence and medical guidance on antioxidant and folinic acid supplementation, explaining why this treatment is not recommended based on clinical trials

Overview

UK perspective and guidance from DSMIG (2018): Dr Jill Ellis, a paediatrician and member of the UK DSMIG, was the lead researcher in the UK on a trial to assess its effectiveness.

Here is the journal paper: Supplementation with antioxidants and folinic acid for children with Down Syndrome: randomised controlled trial.

Objectives: To assess whether supplementation with antioxidants, folinic acid, or both improves the psychomotor and language development of children with Down Syndrome. Design a randomised controlled trial with two by two factorial design.

Here is Jill Ellis talking about it on YouTube. An excellent summary and presentation of their research study: Dr Jill Ellis - Vitamins & Minerals for Children with Down Syndrome 2006.

Here is the Down's Syndrome Association statement: Targeted Nutritional Therapy | Down's Syndrome Association.

So in conclusion, we do not support this treatment and do not believe it has any benefits in the short or long term, supported by our own UK-based research trials.

Dr Ella Rachamim, Community paediatrician (2018 conversation and DSMIG Winter conference).