Appendix 20 - Thyroid guidance (updated 2020)

Thyroid function

Venepuncture at age 6months, 1 year and annually thereafter throughout life - To check T4, TSH and thyroid antibodies.  (Guidance changed in Winter 2019 to annual testing and starting at 6 months).

Where the T4 is normal and the child is asymptomatic but there is a mildly raised TSH (less than or equal to 10mu/l) or thyroid antibodies are present re-check after 6months. A specialist opinion may be warranted.

Have a low threshold for testing thyroid function at other times if clinically indicated eg lethargy and/or changes in affect, cognition, growth, or weight. Testing should be continued throughout life.

If a child is already under the endocrinology team on Thyroxine supplements, please leave monitoring of TFT’s with the endocrine team.

Health Series: Thyroid Disorder – a guide for parents

https://www.downs-syndrome.org.uk/about-downs-syndrome/health-and-wellbeing/thyroid/

Thyroid disorder – a guide for professionals

https://www.downs-syndrome.org.uk/for-professionals/health-medical/annual-health-check-information-for-gps/

https://www.dsmig.org.uk/information-resources/guidance-for-essential-medical-surveillance/

https://www.dsmig.org.uk/wp-content/uploads/2019/01/guideline-thyroid-6.pdf